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Increased thrombogenicity in patients with atherosclerosis of the peripheral arteries of the lower extremities: a case-control study.

Increased thrombogenicity in patients with atherosclerosis of the peripheral arteries of the lower extremities: a case-control study. - Changes in the coagulation in patients with peripheral arterial disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON38884
Enrollment
80
Registered
2013-05-06
Start date
2013-11-18
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atherosclerosis Hypercoagulability peripheral arterial disease

Interventions

None listed

Sponsors

Medisch Universitair Ziekenhuis Maastricht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients who have entered the PAD study, as PAD the novo with an EAI

Exclusion criteria

Exclusion criteria: - Patients with known coagulopathies (coagulation disorders) - Pregnancy - Chronic Inflammatory Disorders - Anti-phospholipid syndrome - Malignancies - Systemic anticoagulation (acenocoumarol, fenprocoumon, dabigatran, rivaroxaban)

Design outcomes

Primary

MeasureTime frame
1. Thrombogram* measurement in full-blood and PPP 2. Flow chamber assay 3. Thromboelastometry with added tPA 4. Measurement of Mi-RNA*s

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)