Functional Determinants of Parkinson*s Bradykinesia; A Kinematic, Neurophysiological and Psychophysical Study

Functional Determinants of Parkinson*s Bradykinesia; A Kinematic, Neurophysiological and Psychophysical Study - Bradykinesia

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON38838

Enrollment

Registered

2013-11-13

Start date

2013-11-19

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

morbus Parkinson Parkinson's disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Parkinson's disease

Exclusion criteria

Exclusion criteria: tremor dominance cognitive dysfunction interfering neurological, ophthalmological, psychiatric or musculoskeletal disease

Design outcomes

Primary

Measure	Time frame
4.5.1 Main study parameter/endpoint Relation between: * Duration of the flash lag illusion * Score on bradykinetic UPDRS III items * Movement amplitude, number of movements per second, acceleration and velocity of hand, finger and foot movements * Score on BRAIN test	—

Secondary

Measure	Time frame
4.5.2 Secondary study parameters/endpoints Relation between: * Movement amplitude, number of movements per second, acceleration and velocity of hand, finger and foot movements * Score on BRAIN test * Score on bradykinetic UPDRS III items * Subjective bradykinesia rating (1-10) 1. at end of dose interval 2. at beginning of dose interval 4.5.3 Other study parameters Relation between: * Dominant frequency of EEG background rhythm. * Duration of the flash lag illusion. * Score on bradykinetic UPDRS III items.	—

Measure

Time frame

4.5.2 Secondary study parameters/endpoints Relation between: * Movement amplitude, number of movements per second, acceleration and velocity of hand, finger and foot movements * Score on BRAIN test * Score on bradykinetic UPDRS III items * Subjective bradykinesia rating (1-10) 1. at end of dose interval 2. at beginning of dose interval 4.5.3 Other study parameters Relation between: * Dominant frequency of EEG background rhythm. * Duration of the flash lag illusion. * Score on bradykinetic UPDRS III items.

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Countries

Netherlands

Outcome results