exciteerbaarheid van motor cortex n.v.t.
Conditions
Interventions
Per experimental session, each subject will receive 300 trials of single-pulse
TMS, 60 trials of paired-pulse TMS and approximately 100 single pulses for
determination of the hotspot and rest motor
Sponsors
Universitair Medisch Centrum Sint Radboud
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Only healthy and competent, 18 years or older, men and woman will be recruited. They can be right- and left handed.
Exclusion criteria
Exclusion criteria: With regard to transcranial magnetic stimulation • Epilepsy, convulsion or seizure • Serious head trauma or brain surgery • Large or ferromagnetic metal parts in the head (except for a dental wire) • Implanted cardiac pacemaker or neurostimulator • Pregnancy;With regard to other experimental techniques • Skin diseases at intended electrode sites (EMG);With regard to general experimental requirements • History or current presence of any neurologic or psychiatric disease • Any prescribed medication that can alter cortical excitability (e.g. antiepileptics, tricyclic anti-depressives or benzodiazepines) or can have an influence on the participant*s vigilance or cognitive performance within two weeks prior to participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure in this study is the mean MEP amplitude of the single and paired TMS pulses. | — |
Countries
Netherlands
Outcome results
None listed