A Pilot Study to monitor changes in Rectum Carcinoma during Radiotherapy with multi-parametric MRI

A Pilot Study to monitor changes in Rectum Carcinoma during Radiotherapy with multi-parametric MRI - changes in Rectum Carcinoma during Radiotherapy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON38751

Enrollment

Registered

2013-08-05

Start date

2013-10-22

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rectum carcinoma

Interventions

As part of this research there are five additional MRI scans. Because the first MRI scan made on the same day as the first radiation fraction it does not need a separate baseline MRI scan.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: patients with proven adenocarcinoma in the rectum, receiving radiotherapy of 25 x 2 Gy.

Exclusion criteria

Exclusion criteria: - contra-indications for a MRI exam - patients with prior irradiation or surgery in the pelvic area - patients with WHO performance status more or the same as 2.

Design outcomes

Primary

Measure	Time frame
To establish an estimate on the anatomical variation (position, shape, size) and functional MR parameters of the GTV during radiotherapy treatment.	—

Secondary

Measure	Time frame
Establish the feasibility of radiotherapy treatment planning for the treatment of rectum carcinoma on an MRL. Establish the need of adaptive replanning during the course of treatment on an MRL	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)