Agressief gedrag attacking behaviour Violence
Conditions
Interventions
The intervention group will receive daily a multivitamin and mineral tablet,
during a period of ten weeks. The placebo group will receive an identical
looking tablet containing starch. The baseline
Sponsors
Erasmus MC
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: The pricipal inclusion criteria are: mild intellectual disability ( IQ 50-85) with behavior problems; age 18 till 40, minimum once a week aggressive behavior according to the reports of the care institution, ten week from the beginning of the intervention.
Exclusion criteria
Exclusion criteria: Exclusion criteria are; users of multivitamin supplements, pregnancy, swallowing problems and users of medication with possible interactions with vitamins and minerals: digoxin, ACE-inhibitors methyldopa, sulfasalazin, levothyroxin, colestyramin, tetracycline antibiotics and warfarin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The reduction of aggressive behavior. .Aggression is measured on the basis of a daily score on the Modified Overt Aggression Scale (MOAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| The effect of the supplements on the quality of life. It is also examined whether the effect of nutritional supplements on aggressive behavior is mediated by positive and negative affect. The positive and negative affect is measured daily, using two items derived from the abbreviated Positive And Negative Affect Schedule (PANAS). The Reactive and Proactive Aggression Scale (RePro) is used to distinguish between reactive and proactive aggression. The Intellectual Disability Quality of Life scale is used (IDQOL-16) for measuring the quality of life. The effects are controlled for sex, age, medication, sweets, alcohol consumption and tobacco consumption. | — |
Countries
Netherlands
Outcome results
None listed