attention reward sensitivity
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Written informed consent, Patients implanted with a DBS device for the treatment of Parkinson*s, Age > 18 years, Patients with bilateral electrode implants will only be included if the stimulation can be generated by one external pulse generator (Kinetra, ActivaPC, or ActivaRC), Therapeutic stimulation parameters should be such that the patient does not directly feel the stimulation pulses and thus can be blinded to the stimulation ON/OFF condition, Symptoms do not immediately reoccur when Stimulation is turned off, absence of dementia or major psychiatric illness, patients have to withhold from their PD medication 12 h prior to the experiment.
Exclusion criteria
Exclusion criteria: I- Inability to turn off the stimulator for the duration of the experiment on clinical grounds - Color blindness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main parameters of interest are the reaction time differences in the visual search tasks, and alterations of perceived stimulus presentation onset. Both can be used as a measure to indicate the degree of influence of DBS on reward processing and selective attention. Previous and ongoing studies on healthy observers in our groups show a beneficial effect of monetary reward on reaction times in visual search tasks (Hickey et al. 2010) and perceived stimulus onset in the simultaneity judgement task. In the present study we aim to test both whether DBS changes these effects of monetary reward and whether stimulation could actually replace the monetary reward as source for the observed influence on selective attention. | — |
Countries
Netherlands
Outcome results
None listed