Addiction Substance Use Disorder (SUD)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria addicted patient group: - Diagnoses of Substance Use Disorder (SUD) assessed by psychiatrist - Between 14 and 23 years of age;Participants in the addicted patient group are instructed not to drink caffeine before the experiment. In accordance with the policy of the clinical department where they stay, participants will maintain a sleep schedule of at least 8 hours per night and are not allowed to use alcohol and/or drugs. ;Inclusion criteria non-addicted, non-patient reference group: - Between 14 and 23 years of age;Participants in the non-addicted, non-patient reference group are instructed to sleep enough (7+ hours) and not to drink alcohol or caffeine before the experiment.
Exclusion criteria
Exclusion criteria: Exclusion criteria addicted patient group: Compulsive gaming behavior and/or gambling addiction assessed by psychiatrist.;Exclusion criteria non-addicted non-patient reference group: -Risky level of alcohol (AUDIT-score >= 8) or cannabis use (CUDIT-R-score >= 8) or lifetime use of any hard drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in working memory capacity from pre-test to immediate post-test will be the primary study outcome. Working memory capacity will be assessed with the Span board task (Klingberg 2005). This task is commonly used in research on the effects of cognitive training on working memory capacity. | — |
Secondary
| Measure | Time frame |
|---|---|
| As secundary outcomes we will assess changes (differences between pre-test, first and second post tests) in other aspects of working memory, craving, mood, and delay discounting (preference for small, immediate rewards over large, long-term rewards) and changes (differences between Routine Outcome Assessment when entering the detix clinic and follow-up assessment) in substance use. Other aspects of working memory capacity will be assessed by the following validated computer tasks: Reading Span Task (Daneman, & Carpenter, 1980; Unsworh, Brewer & Spillers, 2009) Drug Stroop task (Carpenter, Schreiber, Church, & McDowell, 2006; Waters, Marhe, Franken, 2012). Substance use, craving and mood will be measured with scores on questionnaires: Substance use questionnaire (including lifetime, 6-month and 30-day frequency measures, Alcohol Use Disorder Identification Test (AUDIT), Cannabis Use Disorder Identification Test (CUDIT), number of non-using days) OCDS (craving for substance use) (de Wildt, 2010; Hendriks, 2012) BDI-II-NL (depression) (Van der Does, 2002) STAI (state anxiety) (Van der Ploeg, 1980) Delay discounting will be measured with the delay discounting task (Robles, Huang, Simpson & McMillan, 2011). | — |
Countries
Netherlands