Sinonasal pathology in children with Cystic Fibrosis

Sinonasal pathology in children with Cystic Fibrosis - SINAS study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON38689

Enrollment

Registered

2013-07-23

Start date

2013-10-21

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cystic Fibrosis mucoviscidosis rhinosinusitis

Interventions

None listed

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: * Confirmed diagnose of Cystic Fibrosis based on genotyping or a positive sweat test * Age * 0 and

Exclusion criteria

Exclusion criteria: * Gross immunodeficiency (congenital of acquired) * Congenital mucociliary problems other than CF (e.g. Primairy ciliary dyskinesia) * ASA syndrome (Samter*s triad; nasal polyps, asthma, and aspirin sensitivity) * Intranasal neoplasia * Systemic vasculitis and granulomatous diseases (e.g. M. Wegener, sarcoidosis, Churg-Strauss syndrome) * Recently (within 1 month) CT-sinus performed

Design outcomes

Primary

Measure	Time frame
Lund-Mackay scores on CT-sinus in children with CF.	—

Secondary

Measure	Time frame
Secondary study parameters will be the outcome of nasal cultures, symptoms of sinonasal disease and anatomic variations in the sinonasal area.	—

Countries

Netherlands

Outcome results