adrenal function hypothalamic-pituitary-adrenal axis
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Healthy children: prepubertal (6-12 years), no use of steroids or medication with a potential effect on steroidmetabolism;Children with asthma: prepubertal (6-12 years), stable asthma (no additional use of medication in previous three months, no use of systemic steroids in previous three months, normal lungfunction (FEV1 >90% of predicted value)
Exclusion criteria
Exclusion criteria: Informed consent not obtained If the child and/or parents refuses to participate or cooperate during the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cortisol levels in hair samples | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between salivary cortisol levels and cortisol levels in hair samples Association between cortisol levels (in saliva and hair) and symptomscore and lungfunction | — |
Countries
Netherlands