Skeletal muscle lipid metabolism Skeletal muscle metabolism The metabolic process of the skeletal muscle
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Male sex - Age 18-30 years - Lean, BMI 18-25 kg/m2 - Healthy - Stable dietary habits - No medication use
Exclusion criteria
Exclusion criteria: - Female sex - Engagement in programmed exercise > 2 hours total per week - Cardiac problems, such as angina pectoris, cardiac infarction and arrhythmias - First degree relatives with type 2 diabetes mellitus - Any medical condition requiring treatment and/or medication use - Unstable body weight (weight gain or loss > 3 kg in the past three months) - Participation in another biomedical study within 1 month prior to the screening visit - Subjects, who do not want to be informed about unexpected medical findings, or do not wish that their treating physician is informed, cannot participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skeletal muscle lipid content before, directly after exercise and 4 h post exercise (determined from muscle biopsies) with or without glucose supplementation. | — |
Countries
Netherlands