Skip to content

Effects of acute elevation of circulating fatty acids on skeletal muscle lipid accumulation in healthy lean young men

Effects of acute elevation of circulating fatty acids on skeletal muscle lipid accumulation in healthy lean young men - Elevated FFA and skeletal muscle lipid content

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON38652
Enrollment
32
Registered
2013-03-28
Start date
2013-05-03
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skeletal muscle lipid metabolism Skeletal muscle metabolism The metabolic process of the skeletal muscle

Interventions

Sponsors

Universiteit Maastricht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Male sex - Age 18-30 years - Lean, BMI 18-25 kg/m2 - Healthy - Stable dietary habits - No medication use

Exclusion criteria

Exclusion criteria: - Female sex - Engagement in programmed exercise > 2 hours total per week - Cardiac problems, such as angina pectoris, cardiac infarction and arrhythmias - First degree relatives with type 2 diabetes mellitus - Any medical condition requiring treatment and/or medication use - Unstable body weight (weight gain or loss > 3 kg in the past three months) - Participation in another biomedical study within 1 month prior to the screening visit - Subjects, who do not want to be informed about unexpected medical findings, or do not wish that their treating physician is informed, cannot participate in the study.

Design outcomes

Primary

MeasureTime frame
Skeletal muscle lipid content before, directly after exercise and 4 h post exercise (determined from muscle biopsies) with or without glucose supplementation.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)