mini-stroke Transient Ischemick Attack (TIA)
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: * Being adult (18 years and older) * Presenting to the GP with a new episode of symptoms suspected of TIA and the GP considering further investigations to confirm or exclude TIA at the TIA outpatient clinic. * A blood sample can be collected within 72 hours after onset of symptoms.
Exclusion criteria
Exclusion criteria: * The patient still has active symptoms or signs suspected of an ongoing ischemic stroke and immediate referral to the neurologist seems indicated. * Valid history taking is impossible because of severe cognitive impairment or insufficient knowledge of the Dutch language. * Patient with a life expectancy of
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the level of a set of biomarkers in a venous blood sample taken within 72 hours after onset of symptoms. Main study endpoint is the definite diagnosis of TIA (reference standard), which will be established by an expert panel consisting of three neurologists using all available diagnostic information including imaging of the brain and 6 months of follow-up. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary parameters: Possible factors influencing doctor*s and patient*s delay Secondary endpoints: - Endpoints during 6months of follow-up: (ischemic) cerebrovascular events, (ischemic) cardiovascular events, and mortality. - Time delay (f.e. time to first of action of the patient, time to GP consultation) | — |
Countries
Netherlands
Outcome results
None listed