exciteerbaarheid van motore cortex en spierresponsen meten nvt
Conditions
Interventions
Each subject will receive 340 trials of single-pulse TMS.
Sponsors
Universitair Medisch Centrum Sint Radboud
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Healthy and aged 18 years or older
Exclusion criteria
Exclusion criteria: With regard to transcranial brain stimulation - Epilepsy, convulsion or seizure (TMS) - Serious head trauma or brain surgery - Large or ferromagnetic metal parts in the head (except for a dental wire) - Implanted cardiac pacemaker or neurostimulator - Pregnancy With regard to other experimental techniques - Skin diseases at intended electrode sites (EMG) With regard to general experimental requirements - History or current presence of any neurologic or psychiatric disease - Any prescribed medication that can alter cortical excitability (e.g. antiepileptics, tricyclic anti-depressives or benzodiazepines) or can have an influence on the participant*s vigilance or cognitive performance within two weeks prior to participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measures in this study are the MEP amplitudes and EMG waveforms as a results of the single TMS pulses. The different electrode pairs will be analysed to find the best measure of individual muscle groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the difference of the TMS and peripheral electrical stimulation, we will compare the waveforms of the best electrode pairs. | — |
Countries
Netherlands
Outcome results
None listed