Nocturnal muscle protein synthesis after neuromuscular electrical stimulation in elderly men

Nocturnal muscle protein synthesis after neuromuscular electrical stimulation in elderly men - ES-PROvernight

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON38615

Enrollment

Registered

2013-07-22

Start date

2013-09-04

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Loss of muscle mass Sarcopenia

Interventions

Neuromuscular electrostimulation in one of the two legs

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Written informed consent - Age >= 65 years - Male

Exclusion criteria

Exclusion criteria: - Type II diabetes - All co morbidities interacting with mobility and muscle metabolism of the lower limbs (e.g. arthrosis, arthritis, spasticity/rigidity, all neurological disorders, paralysis, hip/knee surgery). - Use of anticoagulants, blood diseases, allergy for lidocain - Use of NSAIDs and acetylsalicylic acid - Patients suffering from PKU (Phenylketonuria) - Presence of implantable cardioverter defibrillator and/or pacemaker - Performed regular resistance type exercise in the past 6 months - Use of any tools to assist during walking (cane/ crutches/ walker) - (Partial) foot/ leg amputation

Design outcomes

Primary

Measure	Time frame
Muscle protein synthesis, expressed as muscle tracer enrichment	—

Secondary

Measure	Time frame
Plasma tracer enrichment	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)