niet van toepassing niet van toepassing
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: See page 10 and 11 of the protocol: -Gender: female -Age: 18-35 year -BMI: 18.5 - 25.0 kg/m2 -Healthy (as judged by the participant) -Being right handed
Exclusion criteria
Exclusion criteria: See page 11 and 12 of the protocol: -Restraint eating (score > 2.80 ) -Lack of appetite -Having difficulties with swallowing/eating -Usage of an energy restricted diet during the last two months -Weight loss or weight gain of 5 kg or more during the last two months -Stomach or bowel diseases -Diabetes, thyroid disease, kidney disease and other endocrine disorders -Having a history of neurological disorders -Having taste or smell disorders -Having schizophrenia or another serious mental illnesses -Usage of daily medication other than oral contraceptives, Paracetamol or hay fever tablets -Pregnancy during the last 6 months, having the intention to become pregnant or lactating -Smoking on average more than one cigarette/cigar a day -Being allergic/intolerant for products under study -Exclusive consumption of *light* versions of beverages -Avoidance of *light* versions of beverages -Disliking the beverages under study -Working or doing an internship/thesis at the group Sensory science and eating behavior (WUR) -Current participation in other nutrition related or medical research -Having a history of or current alcohol consumption of on average more than 28 units per week -Having a contra-indication to MRI scanning
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters/endpoints are (1) the difference in brain activation between an anticipatory reward and a consummatory reward and (2) the difference in brain activation between a consummatory reward labeled as light versus labeled as regular. | — |
Secondary
| Measure | Time frame |
|---|---|
| The 1st secondary study parameter/endpoint is the correlation between brain activation in response to exposure to an anticipatory or a consummatory reward and reaction times and errors (push/pull measure). In addition, two groups will be made based on the product choice outcome and anticipatory reward responses and consummatory reward responses are compared between those groups (i.e. there is looked at the group*reward response interaction). The 2nd secondary study parameter/endpoint is the correlation between brain activation in response to exposure to an anticipatory or a consummatory reward and subject characteristics like reward sensitivity, delayed discounting, impulsivity, health attitude, stress, executive functioning and food neophobia. | — |
Countries
Netherlands