Effects of aprepitant (Emend ®) on the pharmacokinetics of fentanyl.

Effects of aprepitant (Emend ®) on the pharmacokinetics of fentanyl. - Effects of aprepitant (Emend ®) on the pharmacokinetics of fentanyl.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON38557

Enrollment

Registered

2013-08-07

Start date

2014-03-31

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer pain

Interventions

admission of 3 tablets aprepitant (125mg, 80mg, 80mg) (according standard anti-emetic therapy in higly ematogenic chemotherapy)

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: age >= 18 stable use of fentanyl patch written informed consent

Exclusion criteria

Exclusion criteria: using fentanyl as rescue medication intolerance for aprepitant

Design outcomes

Primary

Measure	Time frame
AUC, clearance	—

Secondary

Measure	Time frame
pain score (according Numerical Rating Scale) side effects (according CTC toxicity criteria)	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)