Assessment of normal values of Esophagogastric Junction (EGJ) distensibility in healthy volunteers

Assessment of normal values of Esophagogastric Junction (EGJ) distensibility in healthy volunteers - EGJ distensibility in healthy volunteers

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON38531

Enrollment

Registered

2013-12-23

Start date

2014-02-14

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

EGJ compliance esophagogastric junction (EGJ) distensibility

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. No history of gastrointestinal disease, specially GERD 2. BMI = 18-30 kg/m² 3. Caucasian race 4. Subject signed the informed consent form and is able to adhere to study protocol

Exclusion criteria

Exclusion criteria: age 65 years, co-morbidities (cardiopulmonary disease, collagen diseases, obesity, coagulation disorders and co-morbidity hindering a gastroscopic procedure), previous oesophageal or gastric surgery, patients using anticoagulants, patients unable to give informed consent. Smoking. History of alcohol abuse or current excessive alcohol consumption (> 2 alcoholic beverages per day or > 14 alcoholic beverages per week)

Design outcomes

Primary

Measure	Time frame
The primary objective of this study is to assess normal values of EGJ distensibility in healthy volunteers. Endpoint: EGJ distensibility as assessed with the EndoFLIP system	—

Secondary

Measure	Time frame
This study has no secondary objectives/endpoints.	—

Countries

Netherlands

Outcome results