atopic dermatitis
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Clinically diagnosed atopic dermatitis Mild to moderate atopic dermatitis At least two symmetrical (i.e. left and right side of the body) skin sites with comparable atopic dermatitis severity Age between 18 and 70 years
Exclusion criteria
Exclusion criteria: - Other skin disease other than AD. - Use of antihistamines prior to (72 hours) the study and/or expected use during the study. - Use of antibiotics prior to (4 weeks) the study and/or expected use during the study. - Use of inflammation suppressing medicines (e.g. corticosteroids, NSAIDs) prior to (4 weeks) the study and/or expected use during the study - Use of systemic suppressing drugs (e.g. prednisone, methothrexate) prior to (4 weeks) the study and/or expected use during the study -Severe disorders within the last 6 months before study (e.g. cancer, acute cardiac or circularity disorders, HIV, infectious hepatitis) - Investigator's uncertainty about the willingness or ability of the patient to comply with the protocol requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome parameter in this study is transepidermal water loss (TEWL) as an effect parameter for the skin barrier function Erythema (skin redness) for the extent of skin inflammation | — |
Secondary
| Measure | Time frame |
|---|---|
| Change of severity of atopic dermatitis Skin hydration Change in itching The amount of used cream/ointments (per day and total) Experiences of the subjects on different ointments and effect on skin / eczema symptoms. | — |
Countries
Netherlands
Outcome results
None listed