Congenital aderenal hyperplasia
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Sint Radboud
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: CAH due to 21-hydroxylase deficiency, biochemical and genetically proven Age: 1-16 years
Exclusion criteria
Exclusion criteria: CAH due to other enzym deficiency Refusal to participate by patient/parents Known co-morbidity: cardiac disease, renal disease, co-medication that interferes with blood pressure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparisson of the different cardiovascular riskfactors between CAH patients and reference values. - Insulin resistance - left ventricular hypertrophy - intima media thickness - body composition - 24-h systolic and diastolic bloodpressure - 24-h urinary steroid profile - circulating biochemical risk markers (e.g. lipids) | — |
Secondary
| Measure | Time frame |
|---|---|
| - | — |
Countries
Netherlands
Outcome results
None listed