Changes in Microvascular perfusion, Exercise Tolerance and Perioperative Hemostasis after Treatment with Intravenous Iron of Patients with Mild Anemia Undergoing Arterial Vascular Surgery

Changes in Microvascular perfusion, Exercise Tolerance and Perioperative Hemostasis after Treatment with Intravenous Iron of Patients with Mild Anemia Undergoing Arterial Vascular Surgery - IronVasc study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON38492

Enrollment

Registered

2013-12-17

Start date

2014-01-14

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vascular disease vascular surgery

Interventions

Ferinject or placebo injection

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adult subjects (age 18-85 years) Elective vascular surgery Type of anemia that can be treated by iron injections Preoperative hemoglobin levels of 13 - 10 g/dL or 8.1 - 6.2 mmol/L in males and 12 - 10 g/dL or 7.5 - 6.2 mmol/L in females. Informed consent

Exclusion criteria

Exclusion criteria: Re-operation Emergency operation Pregnancy Patients that are scheduled to receive any form of anemia treatment Patients with a contraindication for receiving iron Patients with COPD or asthma Patients with severe renal failure or renal replacement therapy

Design outcomes

Primary

Measure	Time frame
Changes in exercise tolerance (submaximale bicycle test)	—

Secondary

Measure	Time frame
Microvascular perfusion (intravital microscopic imaging of the sublingual microvasculature) Perioperative hemostasis (blood samples)	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)