dynapenia decrease in muscle function with age dynapenia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Old adults, age 65 years and older, with low mobility and a SPPB score of 6-9;Healthy young adults, age 20-25
Exclusion criteria
Exclusion criteria: - Cardiovascular disorders that causes risk with exercise. - High bloodpressure that is uncontrolled by medication (>180/115) - Previous stroke - Parkinson disease, - Alzheimer or other forms of dementia - Any type of Cancer that is currently been treated or has been treated within 3 months before participation to the study - Pulmonary pathologies that cause risks with exercise(severe asthma, chronic bronchitis) - Musculoskeletal disorders that disables a person from normal walking - Joint replacements in the lower extremity - Severe diabetes involving neuropathy - Visual impairments that disables normal mobility - Smoking, or smoked within one year before participation to the study - BMI higher than 30 kg/m2. - Written informed concent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measures are gait speed and muscle strength. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures are kinematic and kinetic gait characteristics, including step length, stride duration, joint torques, joint powers and EMG. | — |
Countries
Netherlands