Genetic origin of recurrent hydatidiform moles

Genetic origin of recurrent hydatidiform moles - Genetic origin of hydatidiform moles

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON38464

Enrollment

Registered

2013-05-10

Start date

2013-04-01

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

molar pregnancy

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: objective 1: - patients with a history of at least two or more hydatidiform moles;objective 2: - patients from objective 1 without a known mutation in NLRP7 or KHDC3L

Exclusion criteria

Exclusion criteria: objective 1: - patients with a history of less than two molar pregnancies;objective 2: - patients from objective 1 with a mutation in NLRP7 or KHDC3L

Design outcomes

Primary

Measure	Time frame
1) To determine the frequency of mutations in NLRP7 or KHDC3L in patients with recurrent hydatidiform moles in the Netherlands. 2) To identify additional candidate genes associated with (familial) recurrent HM.	—

Secondary

Measure	Time frame
Not applicable.	—

Countries

Netherlands

Outcome results