Antimicrobial effect and penetration of silver from silver garments

Antimicrobial effect and penetration of silver from silver garments - Silver-containing textiles and the skin

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON38442

Enrollment

Registered

2013-03-12

Start date

2013-06-28

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atopic Dermatitis / Atopic Eczema

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1) Age between 18 and 55 years 2) Caucasian race of Western European origin

Exclusion criteria

Exclusion criteria: 1) Systemic inflammation disease other than AD 2) Skin disease other than AD or contact eczema 3) Use of antihistaminics or inflammation-suppressing medication (e.g. corticosteroids, NSAIDs) or antibiotics one month prior to, and during the investigation 4) Sunbathing or using a tanning bed during 2 months prior to, and during the investigation

Design outcomes

Primary

Measure	Time frame
The following parameters will be measured: 1. Total concentration and size of Ag particles in different layers of the stratum corneum harvested by adhesive tape stripping. 2. Concentration of inflammatory mediators (including IL-1a, Il-1RA, and IL-8) in the stratum corneum harvested by adhesive tape stripping 3. Concentration of Ag in urine 4. Density of Staphylococcus aureus on the skin surface, sampled by using cotton swabs.	—

Measure

Time frame

The following parameters will be measured: 1. Total concentration and size of Ag particles in different layers of the stratum corneum harvested by adhesive tape stripping. 2. Concentration of inflammatory mediators (including IL-1a, Il-1RA, and IL-8) in the stratum corneum harvested by adhesive tape stripping 3. Concentration of Ag in urine 4. Density of Staphylococcus aureus on the skin surface, sampled by using cotton swabs.

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Countries

Netherlands

Outcome results