Sodium Bicarbonate versus Saline for the prevention of Contrast Induced Nephropathy in patients undergoing CT-angiography.

Sodium Bicarbonate versus Saline for the prevention of Contrast Induced Nephropathy in patients undergoing CT-angiography. - The Saliña study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON38407

Enrollment

547

Registered

2009-09-21

Start date

2010-01-13

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute renal failure following contrast injection Contrastnephropathy

Interventions

• Group 1: Prehydratie with sodium bicarbonate 1.4% 3 ml/kg bodyweight 1 hour prior to CT-angiography. • Group 2: Pre- and posthydration with saline 0.9% 1 ml/hour/kg bodyweight both during 12 hour

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: eGFR

Exclusion criteria

Exclusion criteria: - age

Design outcomes

Primary

Measure	Time frame
• CIN defined as an increase in serum creatinine > 25% or > 44 µmol/l after 3-5 days. • CIN defined as an increase in serum creatinine > 25% or > 44 µmol/l after 2 months or an indication for dialysis.	—

Secondary

Measure	Time frame
• loss of renal function, calculated as an absolute decrease in eGFR.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)