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DiPAR: Diagnosing Parkinson*s Disease by neuromuscular function evaluation

DiPAR: Diagnosing Parkinson*s Disease by neuromuscular function evaluation - DiPAR

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON38380
Enrollment
90
Registered
2011-03-22
Start date
2012-02-22
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

movement disorders Parkinson's disease

Interventions

None listed

Sponsors

Universitair Medisch Centrum Groningen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: All subjects - right*handed - informed consent - ability to hold a pen for at least half an hour PD patients - diagnosis according to the UK Parkinson*s Disease Society Brain Bank clinical diagnostic criteria - symptoms scored as Hoehn & Yahr I*III - age: >50 years Essential tremor - diagnosis according to the criteria defined by the Tremor Investigation Group for more than 5 years Enhanced physiological tremor - diagnosis based on polymyography Psychogenic tremor - diagnosis based on polymyography Dystonia (writer*s cramp or torticollis spasmodica) - clinical diagnosis of dystonia - last botulinum toxin treatment at least 2 months prior to study investigation Post*stroke spasticity - clinical diagnosis of post*stroke spasticity (afflicting at least right hand function)

Exclusion criteria

Exclusion criteria: All subjects - (other) neurological or motor disorder (than that included for) - Mini Mental State Examination (MMSE) score

Design outcomes

Primary

MeasureTime frame
Pen tip motion, velocity and acceleration and pen grip forces (in the time and frequency domain) during each of the tasks, compared between groups. In addition mean EMG, EMG variability and EMG power peaks will be assessed.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)