The role of gut microbiota and chronic inflammation as drivers of cardiovascular disease - Nijmegen Biomedical Study - Non Invasive markers of Atherosclerosis 3

The role of gut microbiota and chronic inflammation as drivers of cardiovascular disease - Nijmegen Biomedical Study - Non Invasive markers of Atherosclerosis 3 - NBS-NIMA3

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON38378

Enrollment

500

Registered

2014-04-28

Start date

2014-05-08

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atherosclerosis cardiovascular disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - participant NIMA-NBS 2 study - body mass index > 27 kg/m2

Exclusion criteria

Exclusion criteria: - Recent cardiovascular event (myocardial infarction, transient ischemic attack, stroke 1.6) - Renal dysfunction (estimated glomerular filtration rate

Design outcomes

Primary

Measure	Time frame
Descriptive data: Questionnaires DNA: Gene polymorphisms at DNA level Transcriptome: RNA expression in blood and adipose tissue Metabolome: Small molecule metabolites in blood en urine Microbiome: Presence of groups of bacteria Phenotype: Measures of atherosclerosis, adiposity, hepatic steatosis Functional data: Cytokine production by adipocytes, monocytes Follow-up data: Cardiovascular events registry	—

Measure

Time frame

Descriptive data: Questionnaires DNA: Gene polymorphisms at DNA level Transcriptome: RNA expression in blood and adipose tissue Metabolome: Small molecule metabolites in blood en urine Microbiome: Presence of groups of bacteria Phenotype: Measures of atherosclerosis, adiposity, hepatic steatosis Functional data: Cytokine production by adipocytes, monocytes Follow-up data: Cardiovascular events registry

—

Secondary

Measure	Time frame
-	—

Countries

Netherlands

Outcome results