Hamartomatous intestinal polyposis polyps-and-spots syndrome
Conditions
Interventions
MR enteroclysis (MRE) uses magnetic resonance imaging (MRI), without the use of
radiation, and enteroclysis. Contrast medium is infused in the intestine via a
naso-enteric tube by which maximal lumi
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients >= 18 years; Patients who are willing and able to give informed consent.
Exclusion criteria
Exclusion criteria: Inability to provide informed consent; General contraindications to MR imaging (pacemaker or cardioversion device, claustrophobia, certain implanted metallic devices); Patients with known contrast allergy; Abdominal surgery in the 6 weeks prior to inclusion; Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic yield of DBE and MRE, including number, location and size of polyps in the small bowel of PJS patients. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Quality of life and patients' appreciation of MRE and DBE; - The need for DBE if MRE will be the primary surveillance method (for polyps >= 15 mm); - Detection of significant extra-intestinal lesions with MRI; - Total costs of both procedures; - Complication rate of both procedures. | — |
Countries
Netherlands
Outcome results
None listed