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Fast-track thyroidectomy and I-131 radioiodine ablation therapy in patients with differentiated thyroid cancer.

Fast-track thyroidectomy and I-131 radioiodine ablation therapy in patients with differentiated thyroid cancer. - FASTHYNA trial

Status
Unknown
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON38352
Enrollment
70
Registered
2012-07-30
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid cancer

Interventions

70 patients will be randomly allocated to either A) thyroidectomy directly followed by RIT (fast-track protocol (n=35), or B) thyroidectomy followed by a 4 week waiting period before RIT (standard t

Sponsors

Universitair Medisch Centrum Utrecht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Patients with papillary thyroid cancer, stage T1-3N0-1M0 2. Patient planned for total thyroidectomy

Exclusion criteria

Exclusion criteria: 1. T4 or M1 tumours 2. Patients with differentiated thyroid cancer other than papillary or follicular variant of papillary thyroid cancer (= follicular thyroid cancer, Hurthle cell carcinoma or tall cell carcinoma) 3. Incapacitated patients 4. Pregnant patients 5. Patients with detectable Tg antibodies at 1 year follow-up will be excluded for analysis 6. Contrast enhanced CT performed

Design outcomes

Primary

MeasureTime frame
Reduction of sick-leave time—

Secondary

MeasureTime frame
Secondary outcomes will be quality of life, societal costs and efficacy of the treatment.—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)