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Learning, Memory and Networks in the Human Brain: Single Neuron Recordings in Depth-electrode Candidates for Epilepsy Surgery

Learning, Memory and Networks in the Human Brain: Single Neuron Recordings in Depth-electrode Candidates for Epilepsy Surgery - Single Neuron Characteristics in Epilepsy Surgery Candidates

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON38351
Enrollment
15
Registered
2009-09-02
Start date
2010-03-01
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epilepsy seizures

Interventions

None listed

Sponsors

Vrije Universiteit Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Epilepsy patients with macroelectrode and microwire implants. No specific inclusion criteria for the study population apply additional to the standard clinical criteria for the indication of depth electrodes, other than written informed consent.

Exclusion criteria

Exclusion criteria: Hypertension in the medical history of the patient or the use of anti-hypertensive medication.

Design outcomes

Primary

MeasureTime frame
The main study parameters are the macro- and microelectrode recordings, assessing functional connectivity (SL and PLI) and neuronal brain networks (cluster coefficient and path length), seizure frequency and epilepsy burden.

Secondary

MeasureTime frame
These includes the test results of the patients memory and attention tests.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)