Can heating prevent hyperglycaemia-induced endothelial dysfunction?

Can heating prevent hyperglycaemia-induced endothelial dysfunction? - Heating, hyperglycaemia and endothelial dysfunction

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON38281

Enrollment

Registered

2013-12-24

Start date

2014-01-07

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

impaired vessel function after a meal post-prandial endothelial dysfunction

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Diabetes group: - Older than 40 years - Diagnosed with type 2 diabetes mellitus at least 2 years ago Control group: - Older than 40 years

Exclusion criteria

Exclusion criteria: Diabetes group: - Women - Cardiovascular disease - Hypercholesterolemia - Hypertension (>160 mmHg systolic and/or >90 mmHg diastolic pressure) and/or subjects on antihypertensive drugs - Smoking - Type I diabetes mellitus - Older than 70 years - Subjects with vascular complications due to type 2 diabetes mellitus (e.g. diabetic foot ulcer);Control group: - Women - Cardiovascular disease - Hypercholesterolemia - Hypertension (>160 mmHg systolic and/or >90 mmHg diastolic pressure) and/or subjects on antihypertensive drugs - Smoking - Older than 70 years

Design outcomes

Primary

Measure	Time frame
The change in endothelial function after 75-gr glucose (measured as the brachial artery flow-mediated dilation at 3 distinct time-points).	—

Secondary

Measure	Time frame
blood flow (in mL/min)	—

Countries

Netherlands

Outcome results