Acute Kidney Injury in critically ill infants

Acute Kidney Injury in critically ill infants - AKI in critically ill infants

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON38246

Enrollment

390

Registered

2010-04-29

Start date

2010-06-01

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury

Interventions

None listed

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: - Age: Up to 12 months - Group 1: - Patients admitted for minor surgical procedures with stable hemodynamics and normal kidney function: term up to 1 year of age - Group 2: - Critical illness: mechanical ventilation - Need for vasopressor drugs - Group 3: - Critically ill patients with ECMO treatment - Group 4: - Neonates admitted for minor surgical procedures with stable hemodynamics and normal kidney function: 32 up to 37 weeks of gestational age

Exclusion criteria

Exclusion criteria: - No informed consent - Pre-existent kidney disease or kidney anomaly on ultrasound - Group 1 and 4: Use of known nephrotoxic drugs, like aminoglycosides pRIFLE score showing AKI - Group 1, 2, 3: Preterm birth - Group 4: Preterm birth before 32 weeks of gestational age

Design outcomes

Primary

Measure	Time frame
1. To assess reference values of a pre-defined set of biomarkers for AKI in surgical infants with normal kidney function. 2. To evaluate the sensitivity and specificity of these biomarkers in predicting AKI as well as the incidence of AKI in critically ill infants.	—

Secondary

Measure	Time frame
None	—

Countries

Netherlands

Outcome results