Randomized trial on chest irradiation in extensive disease small cell lung cancer

Randomized trial on chest irradiation in extensive disease small cell lung cancer - CREST

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON38229

Enrollment

412

Registered

2008-12-11

Start date

2009-02-18

Completion date

Unknown

Last updated

2024-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer small cell lung cancer

Interventions

thoracic irradiation

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 18 years or older Cytologically or histologically proven small cell lung cancer Documented extensive disease before the start of chemotherapy Any response after 4 to 6 cycles of initial chemotherapy

Exclusion criteria

Exclusion criteria: prior radiotherapy to the brain or the thorax evidence of brain metastases or leptomeningeal metastases, pleural metastases or pleuritis carcinomatosa

Design outcomes

Primary

Measure	Time frame
1 year survival	—

Secondary

Measure	Time frame
toxicity pattern of recurrent disease	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)