Effecten van stress in gezonde vrijwilligers Sociale decision making under stress
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Volunteers are eligible if they are 18 years or older and healthy
Exclusion criteria
Exclusion criteria: * smoking (positive urine screen) * any psychiatric disorder * current or past drug use (positive urine screen on the presence of amphetamines (including MDMA), barbiturates, cannibinoids, benzodiazepines, cocaine and opiates), and alcohol use 24 hours prior to testing * present use of any medication which might influence the stress response, including benzodiazepines, psychotropics, beta blockers, ACE inhibitors and any hormonal treatment excluding any hormonal anticonceptives * lack of fluency in the Dutch language * speech impairments;Acute exclusion criteria are: - any acute illness - fever - having a severe cold - physical exertion within the last 2 hours - drink other than water or any food within the last 2 hours - ingestion of coffee or any caffeine-containing drink within the last 4 hours - alcohol use on the testing day (breath alcohol level above 0%)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| • performance on various social decision making tasks | — |
Secondary
| Measure | Time frame |
|---|---|
| • saliva cortisol and alpha amylase response • autonomic heart rate, blood pressure and skin temperature response • saliva immune response • subjective stress response using questionnaires. • Genotype • Epigenetic DNA methylation | — |
Countries
Netherlands
Outcome results
None listed