atherosclerosis vessel wall atheroma
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - 18 years or older - Patients with coronary artery disease, Transient Ischemic Attack (TIA), minor ischemic stroke, abdominal aortic aneurysm, peripheral arterial disease, presenting with symptoms suggestive of an acute coronary syndrome (ACS) and asymptomatic patients with an increased cardiovascular risk.
Exclusion criteria
Exclusion criteria: - pregnancy or possible pregnancy - documented allergic reaction to godalinium - patients with impaired renal fuction (GFR
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1 .Prevalence and distribution of coronary and aortic atherosclerosis The prevalence of atherosclerosis is defined as the total number of atherosclerotic lesions in the coronary arteries and aorta on the baseline 3T MRI scan. 2. Progression (rate of changes) in coronary and aortic atherosclerosis Progression in atherosclerosis can express itself as an increase in the total number of atherosclerotic lesions, geometric measures or the proportion of the vessel wall area occupied by various plaque components. In this study all three variables of atherosclerosis will be used to assess the progression of atherosclerosis. 3. Coronary and aortic atherosclerosis to predict future events The baseline MRI scan will be used to predict future events. With respect to future events, information will be collected concerning non fatal and fatal vascular disease with clear definition. | — |
Secondary
| Measure | Time frame |
|---|---|
| - | — |
Countries
Netherlands
Outcome results
None listed