Huntington's disease
Conditions
Interventions
None listed
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
2 Years to 99 Years
Inclusion criteria
Inclusion criteria: .Individuals with clinical features of HD with a confirmatory family history of HD or with DNA testing results demonstrating the presence of the HD mutation (i.e. a CAG repeat expansion within the HD gene >35 on larger allele) •Individuals without clinical features of HD with DNA testing result demonstrating presence of the HD mutation (i.e. CAG repeat expansion within the HD gene >35 on larger allele) •First-degree relatives (i.e. parents, siblings, or children) of individuals with HD •Second-degree relatives (i.e. grandparents and grandchildren) of participating individuals with HD •Family members of participating individuals from category 1 or 2 who are know not to carry the HD mutation (e.g., spouses)
Exclusion criteria
Exclusion criteria: • Subjects who are unable to understand the study protocol or unable to give informed consent, and have no legal representative. •Participants with choreic movement disorder other than HD.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| There is no fixed end of study as 'Registry' will take place during visits at the out-patient clinic of the department of Neurology or nursing home. The study is imbedded in the network that provides a platform for communication and exchange of views on HD and a basis for research. | — |
Secondary
| Measure | Time frame |
|---|---|
| n.v.t. | — |
Countries
Netherlands
Outcome results
None listed