Ovarian Ageing in type 1 Diabetes Mellitus: the role of vascular factors

Ovarian Ageing in type 1 Diabetes Mellitus: the role of vascular factors - OVADIA study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON38166

Enrollment

310

Registered

2011-01-12

Start date

2011-07-11

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ageing of the ovaries in women with diabetes ovarian ageing in type 1 diabetes

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients: females diagnosed with type 1 diabetes mellitus Controls: healthy age-matched female controls

Exclusion criteria

Exclusion criteria: Induced menopause: surgical (premenopausal hysterectomy and/or bilateral ovariectomy), chemo- or radiation therapy, ovarian surgery and irregular menstrual cycles.

Design outcomes

Primary

Measure	Time frame
Part I: 1. Age specific AMH level 2. Number of antral follicles present in the ovaries 3. Vascular status using the ENDOVAS screening. Part II: 1. Age in years at natural menopause assesed by means of questionnaires	—

Secondary

Measure	Time frame
Part I: 1. Metabolic status 2. Factors associated with early menopause: common genetic variants and auto-immune factors Part II: 1. Metabolic status if present in patient records.	—

Countries

Netherlands

Outcome results