Psoriasis
Conditions
Interventions
Psoriasis patients will be randomised in a control group or for daily use of a
home UV-device, the Sunshower medical. Patients will be monitored in their
PASI-score, quality of life, vitamin D statu
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: * Psoriasis vulgaris diagnosed by a dermatologist * 18 years or above * Informed consent * Patients successfully treated with phototherapy (UVB/TL01) OR after successful local therapy and a history of good clearance after UV/exposure.
Exclusion criteria
Exclusion criteria: * Use of fumaric acid or immunosuppressants now or in the 2 months previous to inclusion. * Active psoriatic arthritis * History of skin cancer * Concurrent photosensitive skin disorders * Planned sunny holidays during the trial * Use of tanning booths (at home or tanning studio) * Use of vitamine D supplement * Pregnancy or actively planning to get pregnant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PASI-, Skindex-29 and DLQI-scores and their differences between groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study parameters: Difference between control group and patients undergoing the home UV-treatment in: - serum levels of 25(OH)D3 - presence of pyrimidine dimers and/or p53-expression in epidermal cells of patients - amount of mometason ointment used - parameters for metabolic syndrome (HbA1c, blood pressure) | — |
Countries
Netherlands
Outcome results
None listed