Imaging disease activity in patients with Graves' orbitopathy using [18F]-FDG-PET/CT - a pilot study

Imaging disease activity in patients with Graves' orbitopathy using [18F]-FDG-PET/CT - a pilot study - GO-PET pilot

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON38026

Enrollment

Registered

2011-12-02

Start date

2012-03-01

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Graves' orbitopathy

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: > 18 years old and signed informed consent Patients with Graves' orbitopathy (3 groups: higly active / moderately active / completely inactive) Euthyroid >= 2 months

Exclusion criteria

Exclusion criteria: Pregancy Uncontrolled diabetes mellitus, or hyperglycemia prior to scan For patients with active disease: currently receiving treatment for orbitopathy, or treatment ended

Design outcomes

Primary

Measure	Time frame
Qualitative assessment of [18F]-FDG uptake in orbital tissue as imaged by the PET/CT scan and comparison of data between subjects (or groups)	—

Secondary

Measure	Time frame
Semi-quantitative analysis of [18F]-FDG uptake as imaged by the PET/CT scan (a standardized uptake value (SUV) is calculated) Clinical Activity Score	—

Countries

Netherlands

Outcome results