Unraveling genetic causes of congenital multiple pituitary hormone deficiencies

Unraveling genetic causes of congenital multiple pituitary hormone deficiencies - MPHDgenes

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON38016

Enrollment

Registered

2014-02-04

Start date

2014-04-24

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital multiple pituitary hormone deficiency (MPHD)

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with congenital MPHD, a pituitary MRI image consisting of an ectopic posterior pituitary gland and an absent or thin pituitary stalk. Parents of abovementioned patients. Parents must be able to read and understand the written information.

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

Measure	Time frame
Detection of genes causing congenital MPHD in patients with an ectopic posterior pituitary gland and absent or thin pituitary stalk.	—

Secondary

Measure	Time frame
Understanding of the molecular and cellular mechanisms leading to congenital MPHD in patients with an ectopic posterior pituitary gland and absent or thin pituitary stalk. Increase our understanding of pituitary development in man.	—

Countries

Netherlands

Outcome results