colon cancer colon carcinoma
Conditions
Interventions
Colonoscopy will be performed at the operating room when patients are under
general anesthesia. When the tumor is localized, their will be one injection
with the fluorescent tracer at the base of th
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Oral and written Informed Consent (IC) - Age 18 years and older - Patients histologically or radiologically suspicion of colon cancer - Regular Pre-operative work-up - Surgical resection of the tumor
Exclusion criteria
Exclusion criteria: - gross lymph node involvement - distant metastases - advanced disease with invasion of adjacent structures - prior colorectal surgery - metastatic or T4 disease discovered during intraoperative staging - contraindications to laparoscopy - rectal cancer - allergy to iodine - Patients at higher risk for anaphylactic reactions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - identification rate of SLN - Number of false-negative SLNs - Number of patients who are upstaged by ultrastaging techniques - Number and status of aberrant lymph nodes - Accuracy: conformity of the SLN status and the regional node status - Number of positive SLNs which are the only positive nodes found. - Number and status of SLNs detected only by the near-infrared scope in vivo and ex vivo - Number and status of SLNs detected only with Patent Blue ex vivo - Number and status of SLNs detected by the near-infrared scope and patent blue in vivo and ex vivo | — |
Secondary
| Measure | Time frame |
|---|---|
| faesibility of the technique | — |
Countries
Netherlands
Outcome results
None listed