Old and well-functioning; Determinants of PReservation Of Function in ELderly

*Old and well-functioning*; Determinants of PReservation Of Function in ELderly - PROFIEL

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON37951

Enrollment

600

Registered

2010-01-12

Start date

2010-02-23

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

decrease in functioning

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Participation in Hamlet or Frailty-study Informed Consent

Exclusion criteria

Exclusion criteria: not applicable

Design outcomes

Primary

Measure	Time frame
The main outcome parameter will be functional status (being able to function independently). It will be measured using the instrument prescribed in the minimal dataset. i.e. KATZ-15, and the physical performance score by Guralnik.	—

Secondary

Measure	Time frame
Use of care which was not planned will also be an important outcome parameter. Characteristics of somatic, functional, cognitive and psychosocial status will be assessed as potential determinants. Somatic status will be characterized with vascular status (large artery stiffness and carotid intima-media thickness) and bone and body fat status (bone mineral density, lean and fat mass, intra-abdominal and peripheral fat). Functional status will be further characterized by hand grip strength, peak flow measurement, six minute walking test and physical activity. Cognitive status will be assessed in the domains of memory, processing capacity and speed, and executive functions. Psychosocial status will be characterized by quality of life, depression, anxiety and panic disorder, and self management ability questionnaires. As much as possible we will not only assess what people are capable of doing, but also what they actually do. Whenever possible we will use similar tests or measurements as were used at the baseline visit, to maximize the potential to study changes over time in addition to the current status.	—

Measure

Time frame

Use of care which was not planned will also be an important outcome parameter. Characteristics of somatic, functional, cognitive and psychosocial status will be assessed as potential determinants. Somatic status will be characterized with vascular status (large artery stiffness and carotid intima-media thickness) and bone and body fat status (bone mineral density, lean and fat mass, intra-abdominal and peripheral fat). Functional status will be further characterized by hand grip strength, peak flow measurement, six minute walking test and physical activity. Cognitive status will be assessed in the domains of memory, processing capacity and speed, and executive functions. Psychosocial status will be characterized by quality of life, depression, anxiety and panic disorder, and self management ability questionnaires. As much as possible we will not only assess what people are capable of doing, but also what they actually do. Whenever possible we will use similar tests or measurements as were used at the baseline visit, to maximize the potential to study changes over time in addition to the current status.

—

Countries

Netherlands

Outcome results