Clinical significance of new OCT parameters in diagnosis and follow-up of primary open angle glaucoma

*Clinical significance of new OCT parameters in diagnosis and follow-up of primary open angle glaucoma* - GLOCT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON37906

Enrollment

240

Registered

2012-07-25

Start date

2012-10-16

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glaucoma ocular hypertension

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Patients with ocular hypertension, suspect glaucoma, early glaucoma and moderate glaucoma, 18 years of age or older • Patients with open anterior chamber angle • VA > 20/30 • Able to perform reliable visual field test • Willing and able to sign the informed consent.

Exclusion criteria

Exclusion criteria: • Media opacities, like cataract, that will make it impossible to make reliable images with the OCT • Hypermetropia more than S+5 dioptres, or myopia more than S-7 dioptres • Presence of other diseases including retinal disorders that may influence visual acuity, visual field testing or the results of structural measurements done by SD-OCT • Presence of signs of secondary glaucoma such as inflammatory or neovascular causes, with the exception of pigment dispersion syndrome and pseudoexfoliation syndrome

Design outcomes

Primary

Measure	Time frame
Sensitivity and specificity of the new SD-OCT parameters will be compare with the sensitivity and specificity of the RNFL thickness measurements and the visual field testing. We will investigate to what extent these new parameters can contribute in differentiating patients from healthy controls, between stages of glaucoma, between patients with a normal and an elevated baseline IOP, and to establish the accuracy to detect progression of glaucoma.	—

Measure

Time frame

Sensitivity and specificity of the new SD-OCT parameters will be compare with the sensitivity and specificity of the RNFL thickness measurements and the visual field testing. We will investigate to what extent these new parameters can contribute in differentiating patients from healthy controls, between stages of glaucoma, between patients with a normal and an elevated baseline IOP, and to establish the accuracy to detect progression of glaucoma.

—

Secondary

Measure	Time frame
- visual acuity - intra ocular pressure - visual field test outcome - RNFL thickness - GCL thickness - lamina cribrosa thickness - peripapillary choroid thickness	—

Countries

Netherlands

Outcome results