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Conditions
Interventions
Participants will receive single pulses of TMS over left or right V1 at the
individual subject*s and target site*s phosphene threshold.
Sponsors
Radboud Universiteit Nijmegen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - 18-45 years old - Right-handed - Normal or corrected-to-normal vision - No history of mental or psychological disorders
Exclusion criteria
Exclusion criteria: - Pacemaker or (history of) heart rhythm disorder - Metal parts in head or mouth* - History of brain surgery - History of epilepsy or first-grade family member with epilepsy - Psychological or neurological disorder - Skin allergies - Pregnancy - Prescription medication - Being treated or having recently been treated by a medical specialist. * with the exception of a wire behind the teeth.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We aim to determine the relation between the amplitude of alpha oscillations and the effect of their phase on visual cortical excitability and phosphene probability. We expect the validation of the *pulsed inhibition theory* postulating that perception is only decreased during the inhibitory phase of the alpha oscillation. | — |
Secondary
| Measure | Time frame |
|---|---|
| In addition to the assessment of visual cortical excitability and perception by means of phosphene probability, the amplitude of simultaneously recorded TEPs will be employed as an additional measure of phase-dependent cortical excitability (Bergmann et al., 2012). | — |
Countries
Netherlands
Outcome results
None listed