Day hospital Mentalization-Based treatment versus Intensive Outpatient Mentalization-Based Treatment for patients with severe borderline personality disorder: A multi-centre head-to-head randomized clinical trial

Day hospital Mentalization-Based treatment versus Intensive Outpatient Mentalization-Based Treatment for patients with severe borderline personality disorder: A multi-centre head-to-head randomized clinical trial - MBT-DOS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON37807

Enrollment

144

Registered

2012-07-26

Start date

2012-03-01

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

borderline personality disorder

Interventions

MBT-DH is provided 5 days/week and includes daily group psychotherapy, weekly individual psychotherapy, and art- and writing therapy. MBT-IOP includes group psychotherapy twice a week and weekly ind

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria are: (a) diagnosis of borderline personality disorder (BPD), i.e., at least 5 BPD traits using the SCID-II (First et al., 1996), (b) 18 years or older, (c) sufficient knowledge of Dutch language.

Exclusion criteria

Exclusion criteria: Exclusion criteria are: (a) responsibility for the care of children younger than 4 years, (b) having a stable job for longer than two years, (c) antisocial personality disorder and a history of severe physical violence, (d) travel time to the MBT-ward more than an hour, (e) chronic psychotic disorder or autism.

Design outcomes

Primary

Measure	Time frame
Primary outcome variables are: a) symptomatic distress (Brief Symptom Inventory; BSI) b) parasuicidal behaviour (self-destructive acts and suicide attempts; SSHI).	—

Secondary

Measure	Time frame
Secondary outcome variables are: a)depressive symptoms (Beck Depression Inventory; BDI) b) DSM-IV axis I & II diagnoses (Structured Clinical Interview for DSM-IV Axis I disorders; SCID-I, and The Structured Clinical Interview for DSM-IV Axis II Personality disorders; SCID-II) c)borderline symptoms (Personality Assessment Inventory-Boderline schaal; PAI-BOR) d)mentalization (Reflective Functioning Questionnaire; RFQ, Reading the Mind in the Eyes Test; RMET, FaceMorph task) e) personality pathology (Severity Indices of Personality Problems Short Form; SIPP-SF, en Dimensional Assessment of Personality Pathology - Short Form; DAPP-SF) f)quality of life (EuroQol 5 dimensions; EQ-5D) g)interpersonal functioning (Inventory of Interpersonal Problems; IIP-32) h) intimate relationships (Experience in Close Relationships; ECR-R en ECR-2010 partner relationships) i) mental health-related functional impairment (Sheehan Disability Scale; SDS) j)treatment adherence (Compliance Rating Scale; CRS) k)addiction and dependence of psychoactive substances (MATE) l)economic evaluation (Trimbos/iMTA questionnaire for Costs associated with Psychiatric Illness deel 1 en deel 2 ; TiC-P deel 1 en deel 2)	—

Measure

Time frame

Secondary outcome variables are: a)depressive symptoms (Beck Depression Inventory; BDI) b) DSM-IV axis I & II diagnoses (Structured Clinical Interview for DSM-IV Axis I disorders; SCID-I, and The Structured Clinical Interview for DSM-IV Axis II Personality disorders; SCID-II) c)borderline symptoms (Personality Assessment Inventory-Boderline schaal; PAI-BOR) d)mentalization (Reflective Functioning Questionnaire; RFQ, Reading the Mind in the Eyes Test; RMET, FaceMorph task) e) personality pathology (Severity Indices of Personality Problems Short Form; SIPP-SF, en Dimensional Assessment of Personality Pathology - Short Form; DAPP-SF) f)quality of life (EuroQol 5 dimensions; EQ-5D) g)interpersonal functioning (Inventory of Interpersonal Problems; IIP-32) h) intimate relationships (Experience in Close Relationships; ECR-R en ECR-2010 partner relationships) i) mental health-related functional impairment (Sheehan Disability Scale; SDS) j)treatment adherence (Compliance Rating Scale; CRS) k)addiction and dependence of psychoactive substances (MATE) l)economic evaluation (Trimbos/iMTA questionnaire for Costs associated with Psychiatric Illness deel 1 en deel 2 ; TiC-P deel 1 en deel 2)

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)