asthma
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: General inclusion criteria: - Males and females aged 6 to 17 years - Parent / guardian must be able to give written informed consent prior to participation in the study, which includes ability to comply with the requirements and restrictions listed in the consent form. Informed consent must be obtained prior to undertaking any study procedures. - Assent should be obtained from all children in the study where appropriate.;For patients with asthma: - Diagnosis of asthma given by specialists (data documented in patient records) according to the GINA guidelines.
Exclusion criteria
Exclusion criteria: - Known underlying respiratory tract disease like congenital airway abnormalities, cystic fibrosis, primary ciliary dyskinesia, bronchopulmonary dysplasia or bronchiectasis. - Known systemic or inflammatory diseases. - History or current evidence of an upper or lower respiratory infection or symptoms (including common cold) within 2 weeks of baseline assessment (assessment should be deferred). - The child has had a exacerbation (requiring ER attendance or hospital admission and /or a course of high dose OCS for at least 3 days duration) within 4 weeks of the baseline assessment (assessment should be deferred).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - asthma control score - VOC*s of breath prints in exhaled air by gas chromatography mass spectrometry (GC-MS) and electronic nose (eNose). - Fractional exhaled Nitric Oxide - FEV1, PEF | — |
Countries
Netherlands
Outcome results
None listed