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Feasibility of dual channel low field TMS as a plasticity modulator: pilot in healthy volunteers

Feasibility of dual channel low field TMS as a plasticity modulator: pilot in healthy volunteers - Dual microTMS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON37761
Enrollment
102
Registered
2012-06-27
Start date
2012-10-25
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fundamental research Not aplocable

Interventions

Two electromagnets are fitted over the EEG/NIRS cap. Magnetic field flux densities

Sponsors

Universitair Medisch Centrum Groningen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Healthy adult volunteers, native Dutch speakers, Age 18-60, right handed

Exclusion criteria

Exclusion criteria: - Psychiatric or neurological disease, present or past - Visual or hearing limitations that can not be corrected for - Brain surgery - Language disorder - Alcohol or drug addiction - Excessive intake of coffee (>10 units per day) or alcohol (>5 units per day); - Recent use (within 1 day) of alcohol - Recent use (within four weeks) of cannabis or any other non-prescription psychopharmaca; - Presence in the body of MRI-incompatible implants, electronic implants (e.g. cardiac pacemakers), or connectors of electronic equipment (e.g. electrodes); - Pregnancy, lactation.

Design outcomes

Primary

MeasureTime frame
The estimated coherence of EEG recordings between electrodes, The change in effective brain connectivity estimated by DCM for EEG.

Secondary

MeasureTime frame
* The ERP from EEG recordings of the *inner speech* task, * The accuracy obtained during the *inner speech* task * The accuracy obtained during the DSST * The differences in concentrations of oxygenated (HBo) and de-oxygenated blood before, during and after the treatment (as estimated from NIRS measurements).

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)