Determining the stability of TRECs - an important measure for thymic activity.

Determining the stability of TRECs - an important measure for thymic activity. - TREC study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON37746

Enrollment

Registered

2012-05-25

Start date

2013-05-02

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T cell dynamics during immune suppression TREC stability

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: kidney transplantation(s); longterm (>10 years) immune suppression by mycophenolate mofetil and/or azathioprine

Exclusion criteria

Exclusion criteria: chronic graft rejection; thymectomy; T cell defect(s) prior to transplantation

Design outcomes

Primary

Measure	Time frame
The stability (and thereby half-life) of TRECs.	—

Secondary

Measure	Time frame
The changes in telomere length of naive T cells in patients treated with the immune suppressives mycophenolate mofetil and/or azathioprine.	—

Countries

Netherlands

Outcome results