Craniofaciale afwijkingen small lower jaw underdevelopment of the lower jaw
Conditions
Interventions
None listed
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: Study Population 1a: - Age between 0 and 3 months - Presence of a congenital mandibular hypoplasia;Study Population 1b: - Age between 3 months and 18 years old - Presence of congenital mandibular hypoplasia;Study Population 2: - Below the age of 18 years - 3D CT-scan of the head as part of regular patient care;Control Population 1a: - Age below 3 months - Presence of cleft palate - No congenital mandibular hypoplasia;Control Population 1b: - Age between 3 months and 18 years old - Presence of cleft palate - Without congenital mandibular hypoplasia;Control Population 2: - Age below 3 months - Presence of an immature breathing pattern, but otherwise healthy
Exclusion criteria
Exclusion criteria: Control Population 2: - Congenital malformation. - Underlying condition that is not known to influence growth.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Outcomes of physical examination: - Length in centimetres. - Head circumference in millimetres. - Weight in kilograms. Outcomes of polysomnography: - Apnea Hypopnea Index (AHI). - Oxygen Desaturation Index (ODI). Outcomes of ENT exam and nasoendoscopy: - Malampatti score. - Cormack-Lehane score. - Sher-classification. Outcomes of measurements on CT-scans: - Distances in millimetres. | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A. | — |
Countries
Netherlands
Outcome results
None listed