Microbiota profiling in pediatric inflammatory bowel disease by means of IS-pro

Microbiota profiling in pediatric inflammatory bowel disease by means of IS-pro - Microbiota profiling in pediatric inflammatory bowel disease

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON37721

Enrollment

Registered

2012-08-02

Start date

2012-09-10

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic intestinal inflammation Inflammatory bowel disease (IBD)

Interventions

harvesting of 3 mucosal biopsies (Ileum, colon and sigmoid)

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: - Age 17 years and below - diagnosis of IBD (Crohn disease and ulcerative colitis) based on regular endoscopy, histology, intestinal MRI, video capsule endoscopy or a combination of these (IBD Working Group ESPGHAN, 2005)

Exclusion criteria

Exclusion criteria: - Proven infectious colitis during the last month as determined by positive stool culture for Salmonella, Shigella, Yersinia, Campylobacter, Clostridium toxins in stools or parasites in stools - Use of antibiotics in the last 3 months prior to inclusion - Use of probiotics in the last 3 months prior to inclusion - Use of immunosuppressive therapy prior to the study - Patients diagnosed with immunocompromised disease (any of various diseases that suppress the immune system)

Design outcomes

Primary

Measure	Time frame
The fecal and mucosal samples will be analysed by means of IS-pro. The obtained intestinal microbiota profiles of the participants will subsequently be analysed in order to get better insight in the composition of the intestinal microbiota of newly diagnosed IBD patients (see study-objectives)	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)