autonome functiestoornis nl. verminderde werking sympathische zenuwstelsel bloodpressure reducement after a meal postprandial hypotension
Conditions
Interventions
The intervention consists of offering 250 ml coffee at T = 0. This coffee is
prepared in a standardized manner and contains 200 mg coffeine.
Sponsors
Medisch Centrum Leeuwarden
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Admitted to the geriatrics in the Medical Centre Leeuwarden Symptoms of hypotension after a meal Normovolemia Cardiac stability Instructive To be able to sit in a chair for two and a half hours To be mentally competent
Exclusion criteria
Exclusion criteria: Dementia or not able to understand the study or not possible to be instructed. To be mentally incompetent If the first measurement without intervention shows no signs of postprandial hypotension. Precency of pathology which results that coffee is not endured or the intake of cafeine is influenced. No stable cardiac situation. Dehydration. If the patient is not used to drink any coffee and doesnot like it
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 30 minutes continuous measurement of systolic blood pressure in mmHg before the meal 30 minutes continuous measurement of diastolic blood pressure in mmHg before the meal maximum systolic blood pressure reduction in mmHg maximum diastolic blood pressure reduction in mmHg duration in minutes when the maximum systolic and diastolic blood pressure reduction caused by PPH occurs . | — |
Secondary
| Measure | Time frame |
|---|---|
| average base value RR before the meal on all patients in mmHg maximum difference average systolic RR with average systolic base value on all patients in mmHg maximum difference average diastolic RR with average diastolic base value on all patients in mmHg average time in minutes after the start meal when maximum RR-differences due to PPH occur. Average duration in minutes when the maximum RR-increase due to coffeine occurs average age of the patients determine how many men and how many women are included. | — |
Countries
Netherlands
Outcome results
None listed