Effect of neuromuscular blockade on global and regional lung aeration in mechanically ventilated children - a pilot study

Effect of neuromuscular blockade on global and regional lung aeration in mechanically ventilated children - a pilot study - Neuromuscular blockade and tidal volume

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON37704

Enrollment

Registered

2012-08-03

Start date

2012-08-03

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute lung injury

Interventions

None listed

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: • Age between 0 and 12 years • Need for neuromuscular blockade defined by the attending physician • Presence of acute lung injury • weight >= 3 kg

Exclusion criteria

Exclusion criteria: • No need for neuromuscular blockade • No acute lung injury • admitted to the neonatal intensive care unit • premature birth with gestational age corrected for post-conceptional age less than 40 weeks • congenital or acquired neuromuscular disorders • severe traumatic brain injury (i.e. Glasgow Coma Scale

Design outcomes

Primary

Measure	Time frame
Differences in global lung aeration as defined by the center of ventilation before and during use of neuromuscular blockade	—

Secondary

Measure	Time frame
Differences in regional lung aeration before and during use of neuromuscular blockade	—

Countries

Netherlands

Outcome results